Commentary: Poliomyelitis and unnecessary injections

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Commentary: poliomyelitis and unnecessary injections.

vaccines to prevent poliomyelitis have been available for 48 years, paralytic disease continues to occur in some areas, as reported by Kohler et al. 1 elsewhere in this issue of the International Journal of Epidemiology. Let us hope that by the 50th anniversary of the development of the first successful polio-myelitis vaccine all transmission of wild-type polioviruses will have ceased. The Worl...

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Unnecessary injections and poliomyelitis in Pakistan.

Pakistan reported 1046 cases of paralytic poliomyelitis in 1992. In 1993, 78% of all children received three doses of Oral poliovaccine (OPV), but there were 1115 cases to the end of September. As it is not feasible to make house to house surveys to check, we do not know how many children with polio fall outside the reports from surveillance centers which are mainly large hospitals. Hospitals h...

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Did India have the world's largest outbreak of poliomyelitis associated with injections of adjuvanted DPT?

The recent report of an explosive outbreak of poliomyelitis in an orphanage in Delhi(l) and the subsequent correspondence(2,3) have highlighted the phenomenon of 'provocation poliomyelitis'. If an intramuscular injection is given during silent poliovirus infection, paralysis may set in within a day or two. In a community in which poliovirus circulation is intensive, children are at increased ri...

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Poliomyelitis: Current Status in Iran and Worldwide

Poliomyelitis (polio) is a highly infectious viral disease, which mainly affects young children. The virus is transmitted by person-to-person spread mainly through the faecal-oral route or, less frequently, by a common vehicle (e.g. contaminated water or food) and multiplies in the intestine, from where it can invade the nervous system and can cause paralysis. Initial symptoms of polio include ...

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Intradermal Immunization of Monkeys with One Set of Injections of Poliomyelitis Virus

1. By means of a single large dose of poliomyelitis virus, distributed at a number of intradermal sites, active immunity has been produced in Macacus rhesus monkeys, as shown by skin neutralization and intracisternal tests. 2. In the small series (four animals) of monkeys so treated, neither abortive nor paralytic signs of experimental poliomyelitis appeared.

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ژورنال

عنوان ژورنال: International Journal of Epidemiology

سال: 2003

ISSN: 1464-3685,0300-5771

DOI: 10.1093/ije/dyg071